Clobazam Mims

Clobazam Mims. Clobazam is extensively metabolised in the liver by CYP3A and to a lesser extent by CYP2C19 and CYP2B6 to active metabolite Ndesmethylclobazam (NCLB) The active metabolite NCLB may substantially contribute to the safety and efficacy of longterm use of clobazam in adjunctive therapy in epilepsy CYP2C19 is the major contributor for the hydroxylation of NCLB to inactive metabolite 4.

N05BA09 clobazam Belongs to the class of benzodiazepine derivatives anxiolytics Used in the management of anxiety agitation or tension Used in the management of anxiety agitation or tension Disclaimer This information is independently developed by CIMS based on clobazam from various references and is provided for your reference only.

Clobazam MIMS online

In a repeated dose study following administration of 10 mg clobazam twice daily for 28 days the level of unchanged clobazam reached a steady state of 333 nanogram/mL within one week whereas the major serum metabolite took 28 days to reach a near steady state level about 8 times higher than that of unchanged clobazam and this was from 83 to 275 times higher than the metabolite level after a.

Clobazam: Indication, Dosage, Side Effect MIMS.com Malaysia

This information is independently developed by MIMS based on Clobazam Oral and is provided for your reference only It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional the information provided by your pharmacist and/or the manufacturer of the medication It may not contain all the available information you require.

Clobazam: Indication, Dosage, Side Effect, Precaution MIMS

By mouth For Child 6–17 years Initially 5 mg daily dose to be increased if necessary at intervals of 5 days maintenance 03–1 mg/kg daily daily doses of up to 30 mg may be given as a single dose at bedtime higher doses should be divided maximum 60 mg per day.