Angiofibroma Nasofaring Juvenile Radiology. This is a classical presentation of juvenile nasopharyngeal angiofibroma This is a histologically benign lesion with very aggressive local behavior It is almost exclusively encountered in adolescent males 1 The most common presenting symptom is painless nasal obstruction or epistaxis however other symptoms may develop depending on the size and extent of the tumor mass.
Juvenile nasopharyngeal angiofibroma (JNA) is a benign neoplasm of the nasopharynx It accounts for 05% of all head and neck tumors occurring in 1 of 150000 individuals Adolescents and young adults between 14 and 25 years are affected and there is a distinct male predominance[1] Author Jashika Adil Shroff Makhasana Meena A Kulkarni Suhas Vaze Adil Sarosh ShroffCited by Publish Year 2016.
Nasopharynx: Juvenile Angiofibroma Radiology Key
IntroductionPathophysiologyImaging ApproachEtiology Juvenile angiofibroma (JAF) is a benign vascular tumor that occurs almost exclusively in adolescent males The etiology of JAF is unknown but it seems to be stimulated by the hormonal surge that takes place in males at the time of adolescence However there are rare reports of JAF occurring in younger and older age groups Occurrence in phenotypic females should lead to a chromosome check JAF arises in the high posterior nasal cavity The specific tissue of origin is not known with certain Prevalence and Epidemiology JAF is a typically benign tumor presenting in the early teens but may present before age 10 years or after age 25 years This diagnosis is in doubt after age 25 years The tumors will stop growing and may recede once patients are in their early 20s The tumors have androgenspecific receptors Clinical Presentation The young male patient will present with unilateral nasal obstruction and/or epistaxis This should prompt imaging by computed tomography (CT) and/or magnetic resonance (MR) Proptosis or cheek swelling are unusual presenting complaints Eustachian tube dysfunction may result in a middle ear presentation Physical examination shows a polypoid mass that is indistinguishable from other polypoid nasal cavity masses especially inflammatory fibroangiomatous polyps (Figs 1891 and 1892) Proptos Anatomy The point of origin for JAF is the mucosa of the high posterior nasal cavity near the sphenopalatine foramen (Figs 1894 and 1895) The critical anatomy is that of the posterior nasal cavity and nasopharynx Detailed knowledge of the sphenopalatine foramen pterygopalatine fossa and central skull base is required for the analysis of these lesions The relationship of the centralized areas of tumor origin to surrounding structures is pivotal This includes the orbital apex and related orbit Techniques and Relevant Aspects Contrastenhanced computed tomography (CECT) and/or contrastenhanced magnetic resonance (CEMR) begin the evaluation CT can be done with a CT arteriogram followed by a delayed set of images Catheter angiography often retains a central role in management and sometimes the diagnosis MR angiography is not useful.
Juvenile nasopharyngeal angiofibroma Radiology Case
Epidemiology Juvenile angiofibroma (JNA) accounts for < 05% of head and neck neoplasms These benign but locally aggressive tumors are found almost exclusively in adolescent males It is believed that the lesion originates in the region of the sphenopalatine foramen at the junction between the posterior nasal fossa and the nasopharynx.
14 Angiofibroma 2012 12 Magnetic Resonance Imaging Medical Imaging
Juvenile nasopharyngeal angiofibroma Radiology Reference
Juvenile nasopharyngeal angiofibroma
Juvenile Angiofibroma Radiology Key
Juvenile nasopharyngeal angiofibromas are a rare benign but locally aggressive vascular tumors that occur almost exclusively in young men On imaging they present as a vividly enhancing softtissue masses centered on the sphenopalatine foramen Given its vascularity prominent flow voids are seen on MRI leading to a salt and pepper appearance.